Effects of periodontal health and related factors on the oral health-related quality of life in type 2 diabetic patients with chronic periodontitis / 华西口腔医学杂志

<p><b>OBJECTIVE</b>To evaluate the oral health-related quality of life (OHRQOL) in type 2 diabetic patients with chronic periodontitis.</p><p><b>METHODS</b>A total of 80 type 2 diabetic patients with chronic periodontitis who had at least 16 teeth and never accept any periodontal therapy in latest one year were recruited. The clinical periodontal index such as probing depth, attachment loss (AL), modified bleeding index, plaque index were obtained with a Williams type periodontal probe. All accepted structured questionnaire interview including the evaluation of OHRQOL.</p><p><b>RESULTS</b>The geriatric oral health assessment index (GOHAI) results demonstrated good content validity, construct validity and responsibility. The periodontal index had positive correlation with the GOHAI scores. Individuals with self-unsatisfied of oral health status, using hypoglycemic drugs, accompanied with serious gingival inflammation and higher AL had relatively poor OHRQOL.</p><p><b>CONCLUSION</b>The OHRQOL of type 2 diabetes with chronic periodontitis and the negative experiences of items listed in GOHAI questionnaire were affected by self-conscious of oral health and periodontal inflammation status.</p>

Combination therapy of periodontal intrabony defects with demineralized freeze-dried bone powder and platelet-rich plasma / 北京大学学报(医学版)

Objective:To evaluate the effect of decalcified freeze-dried bone allograft(DFDBA) and DFDBA with platelet-rich plasma(PRP) in the treatment of periodontal infrabony defects.Methods: Fifteen periodontal infrabony defects(30 sites) in 12 patients with periodontitis(9 patients with chronic periodontitis and 3 patients with aggressive periodontitis) were selected.Three months after initial therapy,they were assigned to either the DFDBA group(10 defects with 20 sites) or the DFDBA with PRP group(5 defects with 10 sites).The patients were evaluated for plaque index(PI),bleeding index(BI),probing depths(PD) and clinical attachment loss(CAL) before the treatment and at 6 months after periodontal bone graft surgery.Results: The PI,BI,PD and CAL in the DFDBA group were 1.7,2.7,6.0 mm and 7.0 mm at baseline;1.5,1.8,3.9 mm and 4.4 mm at the 6 months after periodontal surgery.The PD,CAL and BI in DFDBA with PRP group at baseline were 6.2 mm,7.1 mm and 2.9;3.2 mm,3.6 mm and 1.7 at the 6 months after periodontal surgery.The PI did not change significantly after surgery in both groups.While both groups showed significant improvement(P

Comparative study of the effecs of removing plaque by two toothbrushing methods / 北京大学学报(医学版)

Objective: To compare the effecte of removing plaque by two toothbrushing methods. Methods: Forty subjects were chosen to take part in the randomized、examiner-blind、crossover study. Results: Modified Bass method has better effect of removing plaque, especially that at the central margin than Vertical method(P

The relationship between oral malodor, VSCs levels in the mouth air with periodontitis and tongue coating / 中华口腔医学杂志

<p><b>OBJECTIVE</b>To assess the relationship between oral malodor, volatile sulphur compounds (VSCs) levels in the mouth air and periodontal index; the role of tongue in the production of VSCs and halitosis.</p><p><b>METHODS</b>60 periodontitis patients with oral malodor were included. Oral malodor was estimated by organoleptic method (organoleptic rating, OR); VSCs level measurements before and after cleaning the tongue coating were made with a portable sulphide monitor (halimeter), respectively; periodontal probing depth (PD) and the proportion of PD >/= 4 mm sites, bleeding index (BI) and plaque index (PLI) were examined; tongue coating was estimated with thickness (Tt) and area (Ta) on the dorsal surface of tongue.</p><p><b>RESULTS</b>The correlation was analyzed with Spearman method. There was a significantly positive correlation between OR, VSCs levels and BI, PLI, and Tt, respectively (P < 0.01). OR and VSCs levels was also related with Ta (P < 0.05). There was a weakly correlation between VSCs levels and PD, and the proportion of PD >/= 4 mm sites (r = 0.26, P < 0.05). No correlation between OR and PD, and the proportion of PD >/= 4 mm sites was existed. Reduction of VSCs levels after cleaning tongue coating was statistically significant (t = 10.15, P < 0.01), and also significantly related with thickness and area of tongue coating (P < 0.01).</p><p><b>CONCLUSIONS</b>In present study, OR and VSCs levels were significantly correlated with gingival inflammation (BI), condition of oral hygiene (PLI), and tongue coating. The relationship between OR, VSCs levels and periodontal probing depth was not found obviously. VSCs levels were significantly reduced after cleaning tongue coating, but the percentage of reduction was less than that of the previous studies.</p>

Effects of non-surgical treatment modalities on peri-implantitis / 中华口腔医学杂志

<p><b>OBJECTIVE</b>To evaluate the effects of local-delivery of 25% metronidazol gel and mechanical cleaning using ultrasonic carbon fiber tip on dental implants with peri-implantitis.</p><p><b>METHODS</b>27 implants with peri-implantitis were randomly assigned to receiving either 25% metronidazol gel treatment or carbon fiber tip ultrasonic scaling. All parameters including plaque index (PLI), probing depth (PD) of pocket, sulcular bleeding index (SBI), and BANA enzyme analysis were measured at baseline, 1, 2, 6 and 12 weeks after treatment.</p><p><b>RESULTS</b>Statistically significant decrease (P < 0.05) in SBI, BANA test and PLI occurred in both treatment groups at all time intervals compared to baseline. PD had a decreasing tendency in both groups, but only metronidazole group reached statistically significant level (P < 0.05) at 2 and 6 week intervals compared to baseline. None of the treatment modalities produced any side effects on the implant and peri-implant tissues.</p><p><b>CONCLUSIONS</b>Both 25% metronidazol gel and mechanical cleaning using ultrasonic carbon fiber tip can be safely and effectively used in the treatment of peri-implant diseases.</p>

A survey on periodontal status of patients with metabolic syndrome in a Beijing community / 实用口腔医学杂志

Objective:To survey the periodontal status of patients with metabolic syndrome in a Beijing community,so as to evaluate the relationship between periodontal status and metabolic syndrome.Methods:152 metabolic syndrome(MS)patients,106 post-acute myocardial infarction patients,211 hypertension patients and 56 healthy subjects were involved.Mesial buccal and distal lingual sites per tooth were examined.The periodontal status including plaque index(PLI),bleeding index(BI),probing depth(PD)and attachment loss(AL)as well as missing teeth number were recorded.Results:In male patients,PLI,BI and PD in MS group were higher than that in the other three groups although the mean age and smoking percentage of MS group were the lowest(P

The expression of receptor for advanced glycation end product in gingival tissues of type 2 diabetic patients with periodontitis / 实用口腔医学杂志

Objective:To detect the distribution of the receptor for advanced glycation end products(RAGE) in gingival tissues of patients with non-insulin dependent diabetes mellitus(NIDDM) accompanying periodontitis.Methods:5 patients with chronic periodontitits(CP) and 4 patients with NIDDM accompanying periodontitis were included. Immunohistochemical staining was performed to detect RAGE and tumor necrosis factor ?(TNF-?) expression in gingival tissues.Interleukin 6(IL-6) and TNF-? levels in gingival crevicular fluid and serum of these patients were examined by ELISA.Results:More RAGE cells were observed in the gingival tissus in the patients of NIDDM with CP than in those of CP(P0.05).Conclusion:RAGE may play a role in the destruction of periodontal tissues in NIDDM patients with CP.